Effect of ultra-violet radiations in health and diseases

The term UV is described “beyond violet” according to light spectra and is of three different types: UVC, UVB and UVA. UV radiations act as strong environmental mutagen due to their property of ionisation and inducing chemical reactions and are capable of forming skin diseases like cancer. Skin with its larger surface area comes in…Read more Effect of ultra-violet radiations in health and diseases

Clinical correlation of cancer stem cells in low and high grade glioma of North Indian population

A link to my recent publication: Mohania, R. Acharya, S.K. Kalra, K. Jain, D. Tripathi, S. Chandel, S. Mohania, K. Choudhury, S. Jain, S. Bhalla. Clinical correlation of cancer stem cells in low and high-grade glioma of North Indian population. Ann Oncol (2016) 27 (suppl_6): 41P. DOI:https://doi.org/10.1093/annonc/mdw367.19  

Genetic studies of autosomal dominant polycystic kidney disease in India

An overview of the project I worked with the Ph.D. scholar, providing research assistance thoroughly. ADPKD is a genetically heterogeneous condition with interfamilial and intrafamilial variability. There has been no specific ongoing research in India. Therefore, the study has been conducted to perform mutational analysis of PKD1 and PKD2 genes among 125 ADPKD probands and study…Read more Genetic studies of autosomal dominant polycystic kidney disease in India

Clinical significance of cancer stem cell markers and its proteins in different grades of astrocytoma

A brief of one of the projects I recently worked.  Cancer stem cells are the small population of cells within tumors with capabilities of self-renewal, differentiation, and tumorigenicity; exhibiting the characteristics of both stem cells and cancer cells. The functional and the histopathological distribution of CSCs in different grades of astrocytoma with response to malignancy…Read more Clinical significance of cancer stem cell markers and its proteins in different grades of astrocytoma

Hospital infection Control

An abstract of my recent publication. Kumar Digvijay, Raman Vashistha,Shikha Chandel,Yogesh Gujrati,Easther Rani, Sanjiv Jasuja Abstract: Previous different studies in India reported that transmission of infection to patients occurs through two general routes, airborne and contact. The air has been a major source of infection, because, the air inside the hospital might have acted as…Read more Hospital infection Control

Comparison of Tacrolimus with everolimus or Mycophenolate mofetil or Steroid regimen and their association with Tryptophan metabolism :A Pilot study

An abstract article submitted at ASN 2016 for a pilot study. I performed the Tryptophan metabolism using qRT-PCR for the department of nephrology. Background: Assess graft survival and safety profile at one year. Explore Tryptophan metabolism pathway as a clinical tool to predict graft survival. Methods: All patients received induction therapy with thymoglobulin(3mg/kg). They received…Read more Comparison of Tacrolimus with everolimus or Mycophenolate mofetil or Steroid regimen and their association with Tryptophan metabolism :A Pilot study

Inflammasomes and colorectal cancer: new insights in probiotics

A brief of a postgraduate intern's thesis. I provided research to writing guidance throughout the work. The study was performed to show the therapeutic point of view for future functional food strategy in chemoprevention and cancer growth inhibition from the indigenous probiotic Lactobacillus plantarum CRD7 strain. The study found evident results from enhanced antiproliferative efficacy…Read more Inflammasomes and colorectal cancer: new insights in probiotics